Lassa virus (LASV)-GP2 (clone EBS-I-304), anti-human, other animals

Source:
A BALB/c mouse was immunized with gamma rays inactivated strain LASV.
Fusion partner: Sp2/0.

Specifications:
Lassa virus is a member of the Arenaviridae and causes Lassa fever in predominantly West Afrika. The main reservoir is formed by local rodents. Up to half a million people are estimated to attract the disease yearly and mortality rates may reach as much as 50%. Viral proteins, coded within two ambisense RNA strands, include GP1, GP2, NP, polymerase and Z matrix protein. EBS-I-304 reacts with GP2, which connects the viral envelope to NP and Z matrix proteins found in the core.

Species reactivity:
Positive: (humanand animals subject to infection with)Lassa virus.

Applications:
EBS-I-304 is excellent for immunohistology, immunofluorescence, immunoblotting, immunoprecipitation and ELISA.
ELISA: +
Frozen sections: +
Immunofluorescence: +
Lateral flow: +
Western blot: +

Positive control: Cells, serum or tissues infected with Lassa virus.

References:
- Branco L.M. et al. Virol. J.7:279-298 (2010).
- Ruo S.L et al., J. Gen. Virol.72, 549-555 (1991).