(Mouse) Sox17 Blocking Peptide (C-term)
€363.00
In stock
SKU
AC-BP20861c
Background:
Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.
Other Names:
Transcription factor SOX-17, Sox17, Sox-17
Target/Specificity:
The synthetic peptide sequence is selected from aa 376-389 of HUMAN Sox17
Gene Name: Sox17
Gene ID: 20671
Primary Accession: Q61473
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.
Other Names:
Transcription factor SOX-17, Sox17, Sox-17
Target/Specificity:
The synthetic peptide sequence is selected from aa 376-389 of HUMAN Sox17
Gene Name: Sox17
Gene ID: 20671
Primary Accession: Q61473
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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