MPI (clone ), anti-human, rat
€388.00
In stock
SKU
MB0150
Background:
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Alternative Name:
Phosphohexomutase, Phosphomannose isomerase, PMI, PMI1, CDG1B
Application Dilution: WB: 1:500~2000, ICC: 1:200~500
Specificity: This antibody detects endogenous levels of Mannose Phosphate Isomerase and does not cross-react with related proteins
Immunogen:
Recombinant full length Human MPI.
MW: Predicted band size: 54kDa, Observed band size: 45kDa
Swis Prot.: P34949
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Mouse IgG1. Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib.Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Alternative Name:
Phosphohexomutase, Phosphomannose isomerase, PMI, PMI1, CDG1B
Application Dilution: WB: 1:500~2000, ICC: 1:200~500
Specificity: This antibody detects endogenous levels of Mannose Phosphate Isomerase and does not cross-react with related proteins
Immunogen:
Recombinant full length Human MPI.
MW: Predicted band size: 54kDa, Observed band size: 45kDa
Swis Prot.: P34949
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Mouse IgG1. Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Is Featured? | No |
---|
Write Your Own Review