MUC1 (clone EBS-T-236), anti-human

Source:
A BALB/c mouse was immunized with human milk fat globule membranes.
Fusion partner: Sp2/0.

Specifications:
EBS-T-236 reacts with sugar moieties of MUC1, an apical cell side epithelial marker which is upregulated or switched on in the majority of carcinomas. EBS-T-236 is excellent as solid phase antibody for CA15-3 tumor marker tests, e.g. in combination with DF3 or EBS-T-236 itself as tracer antibody.

Species reactivity:
Positive: human.

Applications:
EBS-T-236 is excellent for immunohistochemistry on paraffin sections, and can be used both as solid phase as well as tracer antibody in MUC1 serum tests. It also works in fluorescence tests and Western blot.
ELISA: +
Flow cytometry: +
Frozen sections: +
Paraffin sections: Citrate
Western blot: +

Positive control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.

References:
- Tsubura, A. et al. Virchows Arch A Pathol Anat Histopathol.407(1): 59-67 (1985).
- Hilkens, J. et al. Cancer Res.46(5): 2582-2587 (1986).
- Hilkens et al. Int J Cancer34(2), 197-206 (1984).
- Zotter et al. Virchows Arch A Pathol Anat Histopathol406(2), 237-51 (1985).
- ISOBM TD-4 Workshop report, Tumor Biol.19(Suppl 1) (1998)