MUC1 (clone VU-13F11), anti-human

Source:
A BALB/c mouse was immunized with 60-mer MUC1 VNTR synthetic peptide conjugated to BSA.
Fusion partner: Sp2/0.

Specifications:
VU-13F11 reacts with the protein core of MUC1, an apical cell side epithelial marker which is upregulated or switched on in the majority of carcinomas. The dominant epitope of VU-13F11 has not yet been determined but is located in the VNTR domain of MUC1 (confirmed by ELISA). VU-13F11 was not included in the ISOBM TD-4 workshop.

Species reactivity:
Positive: human.

Applications:
VU-13F11 is excellent for cryostat sections. It works also in ELISA and fluorescence tests.ELISA: +
Flow cytometry: +
Immunofluorescence: +
Frozen sections: +
Paraffin section: -
Western blot: +

Positive control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.

References:
- Schol D. et al, Tumor Biol. 19(Suppl 1): 35-45 (1998)