MUC3 (clone EBS-T-232), anti-human

Source:
A BALB/c mouse was immunized with synthetic human MUC3 (SIB-35) peptide.
Fusion partner: NS-1.

Specifications:
EBS-T-232 reacts with SITTTE in the VNTR domain of human MUC3. The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (MUC1), 69 base pairs (MC2) and 51 base pairs (MUC3). Cancer cells of colon, breast and stomach, normal cells of salivary gland, breast, lung, and gastrointestinal tract are positive for MUC3.

Species reactivity:
Positive: human.

Applications:
Immunocytochemistry on frozen and paraffin sections. Immunofluorescence tests.
Flow cytometry: +
Frozen sections: +
Immunofluorescence: +
Paraffin sections: Tris/EDTA

Positive control: LS174T cells or colon carcinoma and normal colon tissue.

References:
- Apostolopoulos, V. et al. J. Gastroenterol. Hepatol, 10 (5): 555-561 (1995)