Neomycin::BSA Conjugate

Neomycin::BSA Conjugate

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SKU
BW-41410013
Catalog Number: BW-41410013
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Product Description
Neomycin is an aminoglycoside antibiotic with activity against many Gram-negative and Gram-positive bacteria. It is very ototoxic and is restricted to oral use for intestinal infections. Neomycin binds to ribosomal subunit and inhibits protein synthesis by blocking Ca2+ channels. It is used as a selective agent for the incorporation of the APH3’ gene.

BSA (bovine serum albumin) is conjugated to neomycin (1:73). One or more of the six amine groups in neomycin are directly linked to carboxyl group(s) in BSA. Neomycin has a molecular weight of 908.9 Da and BSA has a molecular weight of 66.4 kDa. The resultant conjugation solution is then buffer-exchanged with 20 mM PBS at a pH of 7.4.

Conjugated BSA-neomycin is used to recognize neomycin-specific antibodies by ELISA and lateral flow based immunoassay. Product can be stored below -20°C for up to 1 year.

Hazmat Shipping : Non-hazardous
Shelf life : 1 year
Storage : -20°C
Brand Name : bioPLUS
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