NFkB p105/p50 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Nuclear factor NF-kappa-B p105 subunit, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing.

Description:
Rabbit IgG polyclonal antibody for Nuclear factor NF-kappa-B p105 subunit (NFKB1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
DKFZp686C01211 antibody, DNA binding factor KBF1 antibody, DNA binding factor KBF1 EBP1 antibody, DNA-binding factor KBF1 antibody, EBP 1 antibody, EBP-1 antibody, EBP1 antibody, KBF1 antibody, MGC54151 antibody, NF kappa B antibody, NF kappabeta antibody, NF kB1 antibody, NFKB 1 antibody, NFKB p105 antibody, NFKB p50 antibody, Nfkb1 antibody, NFKB1_HUMAN antibody, Nuclear factor kappa B DNA binding subunit antibody, Nuclear factor NF kappa B p105 subunit antibody, Nuclear factor NF kappa B p50 subunit antibody, Nuclear factor NF-kappa-B p50 subunit antibody, Nuclear factor of kappa light polypeptide gene enhancer in B cells 1 antibody, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody, p84/NF-kappa-B1 p98 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human NFkB p105(193-208aa KELIRQAALQQTKEMD), different from the related rat sequence by one amino acid and from the related mouse sequence by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.