p53 (Acetyl-Lys379) polyclonal, anti-human, mouse, rat

Specificity:
p53 (Acetyl-Lys379) Antibody detects endogenous levels of total p53 protein only when acetylated at Lys379.

Synonyms: Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53

Immunogen:
The antiserum was produced against synthesized peptide derived from human p53 around the acetylated site of Lys379.

Immunogen Sequence:
344-393Acetyl

Modification Sites: H:K381 M:K375 R:K379

MW (kDa): 43 kDa

NCBI Gene Symbol: TP53

Database Links:
Gene ID: 7157
Swiss Prot No.: P04637
OMIM No.: 133239/151623/161550/191170/202300/211980/260500/275355
Unigene No.: Hs.654481

Application Dilutions: IHC: 1:50~1:100, IF: 1:100~1:500, ELISA: 1:10000

Purification:
The antibody was purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.

Physical Format:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Concentration: 1 mg/ml

Storage: Stable at -20°C for at least 1 year.