PE Anti-Mouse CD127/IL-7RA Antibody [clone A7R34]

Background:
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

Research Area: Cancer, Immunology, Stem cells

Synonyms:
Interleukin-7 receptor subunit alpha, Il7r, IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA, CD127
Swissprot: P16872

Buffer: PBS with 0.05% Proclin300, 1% BSA

Concentration: 0.2 mg/mL

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Alternative for product with catalog number:
135009, 135010, 158203, 158204, 121111, 121112