PE/Cyanine5.5 Anti-Human CD16 Antibody [clone 3G8]

Background:
CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Synonyms:
T-lymphocyte activation antigen CD16, B7-1, B7, BB1
Swissprot: P33681

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.