PE/Cyanine5.5 Anti-Human CD20 Antibody [clone 2H7]

PE/Cyanine5.5 Anti-Human CD20 Antibody [clone 2H7]

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In stock
SKU
E-AB-F1212I
Catalog Number: E-AB-F1212I
Reactivity: Human, Clone: 2H7
Isotype: Mouse IgG2b, κ, Conjugation: PE/Cyanine5.5
Applications: FCM
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Background:
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Research Area: Cancer, Immunology, Stem cells

Synonyms:
Bp35, Leukocyte surface antigen Leu-16, MS4A1, B-lymphocyte surface antigen B1
Swissprot: P11836

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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