PE/Cyanine5.5 Anti-Human CD29 Antibody [clone TS2/16.2.1]

Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.

Research Area: Cancer, Developmental biology, Microbiology, Neuroscience, Signal transduction, Stem cells

Synonyms:
Integrin beta-1, ITB1, Itgb1, Fibronectin receptor subunit beta, VLA-4 subunit beta, CD29
Swissprot: P05556

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.