PE/Cyanine5.5 Anti-Human CD41 Antibody [clone HIP8]

Background:
CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin.

Research Area: Cancer, Cardiovascular, Immunology, Signal transduction, Stem cells

Synonyms:
Integrin alpha-Iib, ITGA2B, GPalpha Iib, GPIIb, Platelet membrane glycoprotein Iib, CD41, GP2B, ITGAB
Swissprot: P08514

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.