PE/Cyanine7 Anti-Human CD28 Antibody [clone CD28.2]

PE/Cyanine7 Anti-Human CD28 Antibody [clone CD28.2]

€0.00
In stock
SKU
E-AB-F1195H
Catalog Number: E-AB-F1195H
Reactivity: Human, Clone: CD28.2
Isotype: Mouse IgG1, κ, Conjugation: PE/Cyanine7
Applications: FCM
Datasheet, Questions? Contact us!
Background:
CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

Research Area: Cancer, Immunology, Stem cells

Synonyms:
PAS2, MNS, HGpMiX, GYPA, GPSAT
Swissprot: P10747

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Alternative for product with catalog number:
302925, 302926
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