PE/Cyanine7 Anti-Human CD45RO Antibody [clone UCHL1]
€0.00
In stock
SKU
E-AB-F1139H
Catalog Number: E-AB-F1139H
Reactivity: Human, Clone: UCHL1
Isotype: Mouse IgG2a, κ, Conjugation: PE/Cyanine7
Applications: FCM
Datasheet, Questions? Contact us!
Reactivity: Human, Clone: UCHL1
Isotype: Mouse IgG2a, κ, Conjugation: PE/Cyanine7
Applications: FCM
Datasheet, Questions? Contact us!
Background:
CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
Research Area: Cancer, Cardiovascular, Immunology, Neuroscience, Signal transduction, Stem cells
Swissprot: P08575
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
304229, 304230
CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
Research Area: Cancer, Cardiovascular, Immunology, Neuroscience, Signal transduction, Stem cells
Swissprot: P08575
Buffer: PBS with 0.05% Proclin300, 1% BSA
Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Alternative for product with catalog number:
304229, 304230
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