PE/Cyanine7 Anti-Mouse CD41 Antibody [clone MWReg30]

Background:
CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.

Research Area: Cancer, Cardiovascular, Immunology, Signal transduction, Stem cells

Synonyms:
Itga2b, GPalpha Iib, CD41, GPIIb
Swissprot: Q9QUM0

Buffer: PBS with 0.05% Proclin300, 1% BSA

Storage:
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Alternative for product with catalog number:
133915, 133916