PEG10 (clone ), anti-human

PEG10 (clone ), anti-human

€388.00
In stock
SKU
MB0036
Catalog Number: MB0036
Size: 50 ul, 100 ulmouse Ig IgG1
Applications: WB, IP

Datasheet
Background:
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter

Alternative Name:
Retrotransposon-derived protein PEG10, Embryonal carcinoma differentiation-regulated protein, Mammalian retrotransposon-derived protein 2, Myelin expression factor 3-like protein 1, Paternally expressed gene 10 protein, Retrotransposon gag domain-containing protein 3, Retrotransposon-derived gag-like polyprotein, Ty3/Gypsy-like protein, EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

Application Dilution: WB: 1:1000, IP: 1:50~1:200

Specificity: This antibody detects endogenous levels of PEG10 and does not cross-react with related proteins

Immunogen:
Recombinant full length Human PEG10.

MW: Predicted band size: 55KDa , Observed band size: 55KDa/95KDa

Swis Prot.: Q86TG7

Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.
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