AKT1/2/3 (phospho-Ser473) polyclonal, anti-human, mouse, rat

Protein Family: Enzymes, Protein Kinases

Pathway and Disease: Cancers, Cell Communication, Cell Growth and Death, Endocrine System, Immune System, Signal Transduction

Description:
RAC-alpha serine/threonine-protein kinase (AKT1) signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors such as PDGF, EGF, and IGF-I. This antibody binds to phospho-AKT1 (Ser473), phospho-AKT2 (Ser474), and phospho-AKT3 (Ser472).

Alternate Names: Phospho-AKT1/2/3 (Ser473), Phospho-AKT1 (Ser473), Phospho-AKT2 (Ser474), Phospho-AKT3 (Ser472), Serine/threonine-protein kinase akt-1, Protein kinase B akt-1, Phospho-PKB, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, C-AKT, AKT1, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, Protein kinase Akt-2, Protein kinase B, beta, PKB beta, AKT2, RAC-gamma serine/threonine-protein kinase, RAC-PK-gamma, Protein kinase Akt-3, Protein kinase B, gamma, PKB gamma, STK-2, AKT3, PKBG

Application Notes: This antibody binds to phospho-AKT1 (Ser473), phospho-AKT2 (Ser474), and phospho-AKT3 (Ser472). E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P31749; P31751; Q9Y243

Antigen: KLH-conjugated synthetic peptide encompassing the phosphorylated Ser473 residue of human AKT1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by antigen-affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.