Progesterone Receptor (clone PR-81), anti-human

Source:
A BALB/c mouse was immunized with recombinant human progesterone receptor protein.

Specifications:
PR-81 is specific to progesterone receptor and shows minimal cross-reaction with other members of the family.Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone.

Species reactivity:
Positive: human.

Applications:
PR-81 is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.
Frozen sections: +
Paraffin sections: Citrate

Positive control: PR positive breast cancer, T47-D cells.

References:
- Press, M. et al. Steroids67(9): 799-813 (2002).
- Mote P. et al. J.Clin. Pathol.54: 624-630 (2001)