Purified Anti-Human CD7 Monoclonal Antibody

Background:
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.

Synonyms:
T-cell antigen CD7, CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, TP41
Swissprot: P09564

Buffer: PBS with 0.05% Proclin300

Concentration: 0.2 mg/mL

Storage:
Store at 2~8℃. Do not freeze.