Purified Anti-Human/Mouse IL-5 Antibody [clone TRFK5]

Background:
IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

Research Area: Immunology,Cancer

Synonyms:
Interleukin-5, IL-5, B-cell differentiation factor I, T-cell replacing factor, TRF
Swissprot: P05113,P04401

Buffer: PBS with 0.05% Proclin300

Concentration: 0.5 mg/mL

Storage:
Store at 2~8°C. Do not freeze.