Purified Anti-Mouse CD40 Antibody [clone FGK4.5/FGK45]
€0.00
In stock
SKU
E-AB-F1028A
Catalog Number: E-AB-F1028A
Reactivity: Mouse, Clone: FGK4.5/FGK45
Isotype: Rat IgG2a, κ, Conjugation: Unconjugated
Applications: FCM
Datasheet, Questions? Contact us!
Reactivity: Mouse, Clone: FGK4.5/FGK45
Isotype: Rat IgG2a, κ, Conjugation: Unconjugated
Applications: FCM
Datasheet, Questions? Contact us!
Background:
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Research Area: Cancer, Cardiovascular, Immunology, Stem cells
Synonyms:
Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5
Swissprot: P27512
Buffer: PBS with 0.05% Proclin300
Concentration: 0.5 mg/mL
Storage:
Store at 2~8°C. Do not freeze.
Alternative for product with catalog number:
102802, 124601, 124602, 102901, 102902
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Research Area: Cancer, Cardiovascular, Immunology, Stem cells
Synonyms:
Tumor necrosis factor receptor superfamily member 5, Cd40, B-cell surface antigen CD40, Bp50, CD40L receptor, CD40, Tnfrsf5
Swissprot: P27512
Buffer: PBS with 0.05% Proclin300
Concentration: 0.5 mg/mL
Storage:
Store at 2~8°C. Do not freeze.
Alternative for product with catalog number:
102802, 124601, 124602, 102901, 102902
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