Purified Anti-Mouse/Human CD11b Antibody [clone M1/70]

Background:
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Research Area: Cancer, Neuroscience, Signal transduction, Stem cells, Tags & Cell Markers

Synonyms:
Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b
Swissprot: P05555,P11215

Buffer: PBS with 0.05% Proclin300

Concentration: 0.5 mg/mL

Storage:
Store at 2~8°C. Do not freeze.

Alternative for product with catalog number:
101201, 101202