Puromycin Dihydrochloride

Puromycin Hydrochloride is the hydrochloride salt form of puromycin, an aminonuclease antibiotic agent isolated from the bacterium Streptomyces alboniger. Toxic to both eukaryotic and prokaryotic cells. Acting as an analog of the 3′ terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. Prevents growth of bacteria, protozoa, algae, and mammalian cells.

Advantages & Features
- Proven performance in described applications.
- Reliable: stringent quality control standards to guarantee lot-to-lot consistency.
- High Quality.

Specifications
- CAS Number: 58-58-2
- Chemical Formula: C22H29N7O5.2HCl
- Molecular Weight: 544.44
- Purity (HPLC): > 98%

Includes
100 mg Puromycin Dihydrochloride

Applications
- Puromycin is widely used in cell biology as a selection antibiotic agent in mammalian cell culture systems.
- Useful in CRISPR/Cas9 mammalian gene editing by selecting for successful Cas9-induced knock-in with Puromycin resistance gene.

Shipping & Storage
Shipped in: Gel Pack.
Storage: -20 °C (NON Frost-Free Freezer).