Separopore® 2B-CL
€0.00
In stock
SKU
BW-20181053
Application:
Separopore® 2B-CL is a cross-linked bioagarose medium for gel filtration and coupling of affinity ligands. Hydrophilic backbone of Separopore® 2B-CL results in low non-specific interactions and high protein recoveries. Separopore® 2B-CL provides an excellent separation of proteins over a wide molecular weight range. Larger volumes available at discounted prices (enquire).
Technical Specifications:
Matrix: Separopore® 2B-CL (crosslinked agarose beads, 2%)
Particle size range: 52 – 165 μm
Molecular weight range: 6 x 104 – 2 x 107
pH stability: 4 – 9
Flow Specifications: 70 – 140 cm / h
Supplied as slurry in 20% ethanol
Chemical stability: Stable to all solutions commonly used in gel filtration including 8M Urea, 6M guanidine hydrochloride
Physical stability: Negligible volume variation due to changes in pH or ionic strength
Sterilization: Chemical
References:
The photophysics of merocyanine 540. A comparative study in ethanol and in liposomes. Photochem Photobiol. (1988) 48: 187-94.
The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface. J Biol Chem. (2000) 275: 25139-45.
Factor XI binding to activated platelets is mediated by residues R(250), K(255), F(260), and Q(263) within the apple 3 domain. Biochemistry. (2000) 39: 316-23.
Heterogeneity of membrane surface proteins in Glanzmann's thrombasthenia. Blood. (1981) 57: 174-81.
Platelet hyperactivity and abnormal Ca2+ homeostasis in diabetes mellitus. Am J Physiol Heart Circ Physiol. (2001) 280: H1480-9.
PAR-1-stimulated factor IXa binding to a small platelet subpopulation requires a pronounced and sustained increase of cytoplasmic calcium. Biochemistry. (2006) 45: 7289-98.
A subpopulation of platelets responds to thrombin- or SFLLRN-stimulation with binding sites for factor IXa. J Biol Chem. (2004) 279: 19854-9.
Identification of a binding site for glycoprotein Ibalpha in the Apple 3 domain of factor XI. J Biol Chem. (2004) 279: 45470-6.
Fluorescence study of binding of adenosine derivatives to phospholipid membranes — effect of serum albumin. Journal of Molecular Structure (2001) 565-566: 209-212.
Related products:
Separopore® 2B (SKU # 20181045)
Separopore® 2B-MB (Macrobeads) (SKU # 20181054)
Separopore® 4B (SKU # 20181031)
Separopore® 4B-CL (SKU # 20181032)
Separopore® 4B-MB (Macrobeads) (SKU #20181033)
Separopore® 6B (SKU # 20181043)
Separopore® 6B-CL (SKU # 20181036)
Separopore® 6B-MB (Macrobeads) (SKU # 20181035)
Usage: bioWORLD's products are supplied for LABORATORY RESEARCH USE ONLY. The product may not be used as a drug, agricultural or pesticidal product, food additive or as a household chemical.
Hazmat Shipping: Non-hazardous
Storage: 2-8°C
Brand Name: bioPLUS™, Separopore®
Separopore® 2B-CL is a cross-linked bioagarose medium for gel filtration and coupling of affinity ligands. Hydrophilic backbone of Separopore® 2B-CL results in low non-specific interactions and high protein recoveries. Separopore® 2B-CL provides an excellent separation of proteins over a wide molecular weight range. Larger volumes available at discounted prices (enquire).
Technical Specifications:
Matrix: Separopore® 2B-CL (crosslinked agarose beads, 2%)
Particle size range: 52 – 165 μm
Molecular weight range: 6 x 104 – 2 x 107
pH stability: 4 – 9
Flow Specifications: 70 – 140 cm / h
Supplied as slurry in 20% ethanol
Chemical stability: Stable to all solutions commonly used in gel filtration including 8M Urea, 6M guanidine hydrochloride
Physical stability: Negligible volume variation due to changes in pH or ionic strength
Sterilization: Chemical
References:
The photophysics of merocyanine 540. A comparative study in ethanol and in liposomes. Photochem Photobiol. (1988) 48: 187-94.
The role of high molecular weight kininogen and prothrombin as cofactors in the binding of factor XI A3 domain to the platelet surface. J Biol Chem. (2000) 275: 25139-45.
Factor XI binding to activated platelets is mediated by residues R(250), K(255), F(260), and Q(263) within the apple 3 domain. Biochemistry. (2000) 39: 316-23.
Heterogeneity of membrane surface proteins in Glanzmann's thrombasthenia. Blood. (1981) 57: 174-81.
Platelet hyperactivity and abnormal Ca2+ homeostasis in diabetes mellitus. Am J Physiol Heart Circ Physiol. (2001) 280: H1480-9.
PAR-1-stimulated factor IXa binding to a small platelet subpopulation requires a pronounced and sustained increase of cytoplasmic calcium. Biochemistry. (2006) 45: 7289-98.
A subpopulation of platelets responds to thrombin- or SFLLRN-stimulation with binding sites for factor IXa. J Biol Chem. (2004) 279: 19854-9.
Identification of a binding site for glycoprotein Ibalpha in the Apple 3 domain of factor XI. J Biol Chem. (2004) 279: 45470-6.
Fluorescence study of binding of adenosine derivatives to phospholipid membranes — effect of serum albumin. Journal of Molecular Structure (2001) 565-566: 209-212.
Related products:
Separopore® 2B (SKU # 20181045)
Separopore® 2B-MB (Macrobeads) (SKU # 20181054)
Separopore® 4B (SKU # 20181031)
Separopore® 4B-CL (SKU # 20181032)
Separopore® 4B-MB (Macrobeads) (SKU #20181033)
Separopore® 6B (SKU # 20181043)
Separopore® 6B-CL (SKU # 20181036)
Separopore® 6B-MB (Macrobeads) (SKU # 20181035)
Usage: bioWORLD's products are supplied for LABORATORY RESEARCH USE ONLY. The product may not be used as a drug, agricultural or pesticidal product, food additive or as a household chemical.
Hazmat Shipping: Non-hazardous
Storage: 2-8°C
Brand Name: bioPLUS™, Separopore®
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