CD150 (SLAMF1) polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6732
Background:
Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP)
Alternative Name:
CD150 antigen, Cdw150, Estm51, Ipo3, MSLAMF1, CD150, CDw150, SLAM,
Application Dilution: WB: 1:500 - 1:2000
Specificity: SLAMF1 polyclonal antibody detects endogenous levels of SLAMF1 protein.
Immunogen:
Recombinant full length Human SLAMF1.
MW: ~ 37,85 kDa
Swis Prot.: Q13291
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Following occupancy of the T cell receptor by antigen, T cell proliferation and lymphokine production are determined by a second costimulatory signal delivered by a ligand expressed on antigen-presenting cells. SLAM (for signaling lymphocyte-activation molecule, also designated CDw150) is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. SAP (for SLAM-associated protein) contains an SH2 domain and functions to inhibit SH-PTP2 recruitment to the SLAM docking site, an activity induced by Fyn phosphorylation of SLAM. Mutations of the SAP gene may be associated with X-linked lympho-proliferative disease (XLP)
Alternative Name:
CD150 antigen, Cdw150, Estm51, Ipo3, MSLAMF1, CD150, CDw150, SLAM,
Application Dilution: WB: 1:500 - 1:2000
Specificity: SLAMF1 polyclonal antibody detects endogenous levels of SLAMF1 protein.
Immunogen:
Recombinant full length Human SLAMF1.
MW: ~ 37,85 kDa
Swis Prot.: Q13291
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review