SMYD2 (clone ), anti-human, mouse
€388.00
In stock
SKU
MB0147
Background:
SMYD2 (SET and MYND domain containing 2), also known as KMT3C, HSKM-B or ZMYND14, is a 433 amino acid protein that contains one SET domain and one MYND-type zinc finger. Expressed at high levels in liver, heart, kidney, ovary and brain, SMYD2 functions as a lysine methyltransferase that, via methylation of p53, may play a role in repressing p53-mediated transcriptional regulation. The gene encoding MSYD2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Alternative Name:
HSKM-B, Histone methyltransferase SMYD2, EC=2.1.1.43, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, KMT3C, HSKM-B, ZMYND14
Application Dilution: WB: 1:1000
Specificity: This antibody detects endogenous levels of SMYD2 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human SMYD2.
MW: Predicted band size: 50KDa , Observed band size: 50KDa
Swis Prot.: Q9NRG4
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
SMYD2 (SET and MYND domain containing 2), also known as KMT3C, HSKM-B or ZMYND14, is a 433 amino acid protein that contains one SET domain and one MYND-type zinc finger. Expressed at high levels in liver, heart, kidney, ovary and brain, SMYD2 functions as a lysine methyltransferase that, via methylation of p53, may play a role in repressing p53-mediated transcriptional regulation. The gene encoding MSYD2 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Alternative Name:
HSKM-B, Histone methyltransferase SMYD2, EC=2.1.1.43, Lysine N-methyltransferase 3C, SET and MYND domain-containing protein 2, KMT3C, HSKM-B, ZMYND14
Application Dilution: WB: 1:1000
Specificity: This antibody detects endogenous levels of SMYD2 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human SMYD2.
MW: Predicted band size: 50KDa , Observed band size: 50KDa
Swis Prot.: Q9NRG4
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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