TBL1 (clone 4H2) , anti-human
€388.00
In stock
SKU
MB0192
Background:
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
Alternative Name:
F-box-like/WD repeat-containing protein, TBL1X, SMAP55, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked, TBL1X, TBL1
Application Dilution: WB: 1:1000, ICC: 1:100~500
Specificity: This antibody detects endogenous levels of TBL1 and does not cross-react with related proteins.
Immunogen:
Purified recombinant human TBL1 protein fragments expressed in E.coli.
MW: Predicted band size: 58KDa , Observed band size: 58KDa
Swis Prot.: O60907
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Mouse IgG2b. Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.
Alternative Name:
F-box-like/WD repeat-containing protein, TBL1X, SMAP55, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked, TBL1X, TBL1
Application Dilution: WB: 1:1000, ICC: 1:100~500
Specificity: This antibody detects endogenous levels of TBL1 and does not cross-react with related proteins.
Immunogen:
Purified recombinant human TBL1 protein fragments expressed in E.coli.
MW: Predicted band size: 58KDa , Observed band size: 58KDa
Swis Prot.: O60907
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Mouse IgG2b. Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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