CD258 (TNFSF14) polyclonal, anti-human, mouse
€305.00
In stock
SKU
BS61000
Background:
Herpes virus entry mediator (HVEM), a type I transmembrane protein, is a member of the TNF receptor superfamily. HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD). HVEM also binds two cellular ligands, secreted lymphotoxin α and light. LIGHT is a member of the TNF superfamily produced by activated T cells. This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM. LIGHT is closely related in sequence to lymphotoxin β (LTβ) and can also bind to the LTβ receptor. LIGHT is also known to induce apoptosis and suppress tumor formation.The gene encoding LIGHT maps to human chromosome 19p13.3.
Alternative Name:
Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, CD258, Cleaved into the following 2 chains, Tumor necrosis factor ligand superfamily member 14, membrane form, Tumor necrosis factor ligand superfamily member 14, soluble form, TNFSF14, HVEML, LIGHT, UNQ391, PRO726
Application Dilution: WB: 1:500~1:1000
Specificity: TNFSF14 polyclonal antibody detects endogenous levels of TNFSF14 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TNFSF14.
MW: ~ 26 kDa
Swis Prot.: O43557
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Herpes virus entry mediator (HVEM), a type I transmembrane protein, is a member of the TNF receptor superfamily. HVEM mediates the entry of herpes simplex virus (HSV) 1 and 2 into T lymphocytes by serving as an attachment site for the HSV envelope glycoprotein D (gD). HVEM also binds two cellular ligands, secreted lymphotoxin α and light. LIGHT is a member of the TNF superfamily produced by activated T cells. This type II transmembrane protein competes with HSV glycoprotein D for binding to HVEM. LIGHT is closely related in sequence to lymphotoxin β (LTβ) and can also bind to the LTβ receptor. LIGHT is also known to induce apoptosis and suppress tumor formation.The gene encoding LIGHT maps to human chromosome 19p13.3.
Alternative Name:
Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L, Herpesvirus entry mediator ligand, CD258, Cleaved into the following 2 chains, Tumor necrosis factor ligand superfamily member 14, membrane form, Tumor necrosis factor ligand superfamily member 14, soluble form, TNFSF14, HVEML, LIGHT, UNQ391, PRO726
Application Dilution: WB: 1:500~1:1000
Specificity: TNFSF14 polyclonal antibody detects endogenous levels of TNFSF14 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TNFSF14.
MW: ~ 26 kDa
Swis Prot.: O43557
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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