CD252 (TNFSF4) polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS61020
Background:
The Ox40 ligand, Ox40L (also designated gp34), is a type II membrane protein, due to the absence of a signal peptide. Ox40L, a member of the tumor necrosis factor (TNF) superfamily, is a costimulatory molecule involved in dendritic cell:T cell interactions, T cell homing and B cell activation. Engagement of Ox40L with its receptor, Ox40, delivers a strong costimulatory signal to effector T cells. Ox40L is found preferentially on activated B cells and its receptor, Ox40, is a member of the tumor necrosis factor receptor (TNFR) family that is expressed on activated T cells. Ox40L plays a critical role in antigen-specific T cell responses in vivo and in both the priming and effector phases of T cell activation when expressed on antigen-presenting cells (APCs).
Alternative Name:
Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, CD252, TNFSF4, TXGP1
Application Dilution: WB: 1:500~1:1000
Specificity: TNFSF4 polyclonal antibody detects endogenous levels of TNFSF4 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TNFSF4.
MW: ~ 15 kDa
Swis Prot.: P23510
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The Ox40 ligand, Ox40L (also designated gp34), is a type II membrane protein, due to the absence of a signal peptide. Ox40L, a member of the tumor necrosis factor (TNF) superfamily, is a costimulatory molecule involved in dendritic cell:T cell interactions, T cell homing and B cell activation. Engagement of Ox40L with its receptor, Ox40, delivers a strong costimulatory signal to effector T cells. Ox40L is found preferentially on activated B cells and its receptor, Ox40, is a member of the tumor necrosis factor receptor (TNFR) family that is expressed on activated T cells. Ox40L plays a critical role in antigen-specific T cell responses in vivo and in both the priming and effector phases of T cell activation when expressed on antigen-presenting cells (APCs).
Alternative Name:
Tumor necrosis factor ligand superfamily member 4, Glycoprotein Gp34, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, CD252, TNFSF4, TXGP1
Application Dilution: WB: 1:500~1:1000
Specificity: TNFSF4 polyclonal antibody detects endogenous levels of TNFSF4 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human TNFSF4.
MW: ~ 15 kDa
Swis Prot.: P23510
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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