TRIM5 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP11747B
Catalog Number: AC-AP11747B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB29688
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB29688
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Other Names:
Tripartite motif-containing protein 5, 632-, RING finger protein 88, TRIM5, RNF88
Target/Specificity:
This TRIM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-399 amino acids from the C-terminal region of human TRIM5.
Antigen Region:
371-399
Antigen Type: Synthetic Peptide
Gene Name: TRIM5
Gene ID: 85363
Primary Accession: Q9C035
NCBI Accession: NP_149023.2;NP_149083.2;NP_149084.2
Other Accession: NP_149083.2;NP_149084.2;NP_149023.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Other Names:
Tripartite motif-containing protein 5, 632-, RING finger protein 88, TRIM5, RNF88
Target/Specificity:
This TRIM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-399 amino acids from the C-terminal region of human TRIM5.
Antigen Region:
371-399
Antigen Type: Synthetic Peptide
Gene Name: TRIM5
Gene ID: 85363
Primary Accession: Q9C035
NCBI Accession: NP_149023.2;NP_149083.2;NP_149084.2
Other Accession: NP_149083.2;NP_149084.2;NP_149023.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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