Troponin I3 (phospho-T142) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS4282
Background:
Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
Alternative Name:
Troponin I, cardiac muscle, Cardiac troponin I, TNNI3, TNNC1
Application Dilution: WB: 1:500~1:1000
Specificity: Troponin I3 (phospho-T142) polyclonal antibody detects endogenous levels of Troponin I3 protein only when phosphorylated at Thr142.
Immunogen:
Synthetic phosphopeptide derived from human Troponin I3 around the phosphorylation site of Thr142.
MW: ~ 28 kDa
Swis Prot.: P19429
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.
Alternative Name:
Troponin I, cardiac muscle, Cardiac troponin I, TNNI3, TNNC1
Application Dilution: WB: 1:500~1:1000
Specificity: Troponin I3 (phospho-T142) polyclonal antibody detects endogenous levels of Troponin I3 protein only when phosphorylated at Thr142.
Immunogen:
Synthetic phosphopeptide derived from human Troponin I3 around the phosphorylation site of Thr142.
MW: ~ 28 kDa
Swis Prot.: P19429
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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