TUBB2A (Acetyl-K379) polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS64103
Background:
Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. g Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and e Tubulin are associated with the centrosome. d Tubulin is a homolog of the Chlamydomonas d Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. e Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.
Alternative Name:
Tubulin beta-2A chain, Tubulin beta class IIa, TUBB2A, Tubulin beta-2B chain, TUBB2B, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3, Tubulin beta-4B chain, Tubulin beta-2 chain, Tubulin beta-2C chain, TUBB4B, Tubulin beta chain, Tubulin beta-5 chain, TUBB, Tubulin beta-6 chain, Tubulin beta class V, TUBB6
Application Dilution: WB: 1:500~1:1000
Specificity: TUBB2A (Acetyl-K379) polyclonal antibody detects endogenous levels of TUBB2A protein only when acetylated at Lys379. This antibody also recognizes TUBB2B/3/4A/4B/6 protein when acetylated at the corresponding residues.
Immunogen:
Synthetic Acetylated peptide derived from human TUBB2A around the Acetylation site of K379.
MW: ~ 49 kDa
Swis Prot.: Q13885/Q9BVA1/Q13509/P04350/P68371/P07437/Q9BUF5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Tubulin is a major cytoskeleton component that has five distinct forms, designated a, b, g, d and e tubulin. a and b tubulins form heterodimers which multimerize to form a microtubule filament. Multiple b Tubulin isoforms (b1, b2, b3, b4, b5, b6 and b8) have been characterized and are expressed in mammalian tissues. b1 and b4 are present throughout the cytosol, b2 is present in the nuclei and nucleoplasm, and b3 is a neuron-specific cytoskeletal protein. g Tubulin forms the gammasome, which is required for nucleating microtubule filaments at the centrosome. Both d Tubulin and e Tubulin are associated with the centrosome. d Tubulin is a homolog of the Chlamydomonas d Tubulin Uni3 and is found in association with the centrioles, whereas e Tubulin localizes to the pericentriolar material. e Tubulin exhibits a cell cycle-specific pattern of localization; first associating with only the older of the centrosomes in a newly duplicated pair, and later associating with both centrosomes.
Alternative Name:
Tubulin beta-2A chain, Tubulin beta class IIa, TUBB2A, Tubulin beta-2B chain, TUBB2B, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3, Tubulin beta-4B chain, Tubulin beta-2 chain, Tubulin beta-2C chain, TUBB4B, Tubulin beta chain, Tubulin beta-5 chain, TUBB, Tubulin beta-6 chain, Tubulin beta class V, TUBB6
Application Dilution: WB: 1:500~1:1000
Specificity: TUBB2A (Acetyl-K379) polyclonal antibody detects endogenous levels of TUBB2A protein only when acetylated at Lys379. This antibody also recognizes TUBB2B/3/4A/4B/6 protein when acetylated at the corresponding residues.
Immunogen:
Synthetic Acetylated peptide derived from human TUBB2A around the Acetylation site of K379.
MW: ~ 49 kDa
Swis Prot.: Q13885/Q9BVA1/Q13509/P04350/P68371/P07437/Q9BUF5
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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