CD106 (VCAM1) (clone ), anti-human, mouse, rat, zebra fish

Background:
The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2α1 and B2αM integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM) -like protein and is deleted in 66% of patients with Kallmann's syndrome, anosmia with secondary hypogonadism .

Alternative Name:
Vascular cell adhesion protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, L1CAM

Application Dilution: WB: 1:1000-1:5000, IHC/ICC/IF: 1:50-1:200, IP: 1:50-1:200

Specificity: This antibody detects endogenous levels of VCAM1 and does not cross-react with related proteins.

Immunogen:
Recombinant antibody.

MW: ~ 81 kDa

Swis Prot.: P19320

Purification & Purity:
Protein A affinity purified

Format:
Recombinant Rabbit Monoclonal Antibody. 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

For research use only, not for use in diagnostic procedure.