KMT3C / SMYD2 monoclonal, anti-human, mouse

KMT3C / SMYD2 monoclonal, anti-human, mouse

€470.00
In stock
SKU
AC-AP53278
Catalog Number: AC-AP55218
Size: 100 µl
Host: Rabbit
Applications: IHC-P, IHC-F, IF, ICC, E
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Background:
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

Other Names:
Histone methyltransferase SMYD2;HSKM B;HSKM-B;HSKMB;KMT3C;Lysine N-methyltransferase 3C; MGC119305;N lysine methyltransferase SMYD2;N-lysine methyltransferase SMYD2;SET and MYND domain containing 2;SET and MYND domain containing protein 2;SET and MYND domain-containing protein 2;Smyd2;SMYD2_HUMAN;Zinc finger MYND domain containing 14;ZMYND14.

Antigen Type: Recombinant Protein

Antigen Type: SMYD2
Gene ID: 56950
Primary Accession: Q9NRG4
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