CD38 (clone HIT2), anti-human

Protein Family: CAM Ligands, Cellular Antigens, Enzymes

Pathway and Disease: Cofactor and Vitamin Metabolism, Immune System, Signal Transduction, Signaling Molecules and Interaction

Description:
The CD38 (HIT2) antibody recognizes a 45-kDa single chain type-II transmembrane glycoprotein expressed on thymocytes, activated T and B cells, hematopoietic progenitors and terminally differentiated B cells/plasma cells (at high levels). CD38 antigen is also present on monocytes, dendritic cells, NK cells and some epithelial cells. CD38 is a NAD glycohydrolase and is a regulator of cell activation and proliferation, and also involved in adhesion between human lymphocytes and endothelial cells.

Alternate Names: CD38, ADP-ribosyl cyclase 1, Cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10

Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500

Accession No.: P28907

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Schlossman S et al. eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York.
[2] Yang CY Et al. 1993. J. Monoclonal Ab. 9(4) :56.
[3] Chen Z et al. 1987. Shanghai J. of Immunol. 7(1) :1