CD4 (clone HIT4a), anti-human
€323.00
In stock
SKU
250936
Catalog Nr.: 250936
Size: 0.1 mg
Isotype: mouse IgG2b
Applications: E, FC
Size: 0.1 mg
Isotype: mouse IgG2b
Applications: E, FC
Protein Family: Cellular Antigens, Cell Adhesion Molecules
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD4 (HIT4a) Antibody recognizes a 55 kDa type-I single-chain transmembrane glycoprotein. CD4 antigen is a coreceptor for HLA class II molecule and HIV (human immunodeficiency virus), which is present on 35-50% of peripheral blood lymphocytes-T helper/inducer (Th/Ti), 70-80% of thymocytes and in low density on the peripheral blood monocytes and tissue macrophages. Th/Ti helps Ig production by B lymphocytes by enhancing maturation and increasing effectiveness of cytotoxic CD8 T cells.
Alternate Names: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4
Application Notes: E: 1:500-1:1,000; FC: 1:200-1:1,000
Accession No.: P01730
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York
Zhang, 2012. DOI: 10.1007/s11033-012-2136-4
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD4 (HIT4a) Antibody recognizes a 55 kDa type-I single-chain transmembrane glycoprotein. CD4 antigen is a coreceptor for HLA class II molecule and HIV (human immunodeficiency virus), which is present on 35-50% of peripheral blood lymphocytes-T helper/inducer (Th/Ti), 70-80% of thymocytes and in low density on the peripheral blood monocytes and tissue macrophages. Th/Ti helps Ig production by B lymphocytes by enhancing maturation and increasing effectiveness of cytotoxic CD8 T cells.
Alternate Names: T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, CD4
Application Notes: E: 1:500-1:1,000; FC: 1:200-1:1,000
Accession No.: P01730
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York
Zhang, 2012. DOI: 10.1007/s11033-012-2136-4
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