CD45 (clone HI30) PE, anti-human
€390.00
In stock
SKU
251081
Catalog Nr.: 251081
Size: 2 ml
Isotype: mouse IgG1
Applications: FC
Size: 2 ml
Isotype: mouse IgG1
Applications: FC
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Enzymes
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD45 (HI30) antibody recognizes the 180, 190, 205 and 220-kDa long single chain type I transmembrane glycoprotein called leukocyte common antigen (LCA). LCA is typically expressed at high levels on all nucleated hematopoietic cells including bone marrow cells, thymocytes, lymphocytes, monocytes, granulocytes, but not on mature erythrocytes, platelets and non-hematopoietic tissues and cells. CD45 is critically required for T and B cell antigen receptor-mediated activation.
Alternate Names: Leukocyte common antigen, L-CA, T200, CD45 antigen, PTPRC, Protein tyrosine phosphatase receptor type C
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08575, NP_002829
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Shen DC., et al. 1991. J. Monoclonal Antibody. 7(1):53
Knapp W., et al., eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD45 (HI30) antibody recognizes the 180, 190, 205 and 220-kDa long single chain type I transmembrane glycoprotein called leukocyte common antigen (LCA). LCA is typically expressed at high levels on all nucleated hematopoietic cells including bone marrow cells, thymocytes, lymphocytes, monocytes, granulocytes, but not on mature erythrocytes, platelets and non-hematopoietic tissues and cells. CD45 is critically required for T and B cell antigen receptor-mediated activation.
Alternate Names: Leukocyte common antigen, L-CA, T200, CD45 antigen, PTPRC, Protein tyrosine phosphatase receptor type C
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08575, NP_002829
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Shen DC., et al. 1991. J. Monoclonal Antibody. 7(1):53
Knapp W., et al., eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
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