CD45RA (clone HI100) PE, anti-human
€390.00
In stock
SKU
251082
Catalog Nr.: 251082
Size: 2 ml
Isotype: mouse IgG2a
Applications: FC
Size: 2 ml
Isotype: mouse IgG2a
Applications: FC
Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens, Enzymes
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD45RA (HI100) antibody recognizes the 205/220-kDa isoform of leukocyte common antigen expressed on 40-50% peripheral CD4+ T cells, 50% peripheral CD8+ T cells and a portion of B cells and monocytes. Studies have shown that expression of different isoforms is characteristic of differentiated subset of hematopoietic cells (for instance CD45RA on naïve/ resting T cells and CD45RD on memory/ activated T cells; CD45RA on medullary thymocytes and CD45RD on cortical thymocytes). It is also reported that the pattern of 87% of B-ALL is CD45RA+/ CD45RO-, 70% of T-ALL is CD45RA-/ CD45RD+ and 78% of B-ALL is CD45RA+/ CD45RO+.
Alternate Names: Leukocyte common antigen, L-CA, T200, CD45 antigen, PTPRC, Protein tyrosine phosphatase receptor type C
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08575
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Shen DC., et al. 1991. J. Monoclonal Antibody. 7(1):53
Knapp W., et al., eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
Pathway and Disease: Immune System, Signaling Molecules and Interaction
Description:
The CD45RA (HI100) antibody recognizes the 205/220-kDa isoform of leukocyte common antigen expressed on 40-50% peripheral CD4+ T cells, 50% peripheral CD8+ T cells and a portion of B cells and monocytes. Studies have shown that expression of different isoforms is characteristic of differentiated subset of hematopoietic cells (for instance CD45RA on naïve/ resting T cells and CD45RD on memory/ activated T cells; CD45RA on medullary thymocytes and CD45RD on cortical thymocytes). It is also reported that the pattern of 87% of B-ALL is CD45RA+/ CD45RO-, 70% of T-ALL is CD45RA-/ CD45RD+ and 78% of B-ALL is CD45RA+/ CD45RO+.
Alternate Names: Leukocyte common antigen, L-CA, T200, CD45 antigen, PTPRC, Protein tyrosine phosphatase receptor type C
Application Notes: FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000
Accession No.: P08575
Format: Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Product Citations:
Shen DC., et al. 1991. J. Monoclonal Antibody. 7(1):53
Knapp W., et al., eds. 1989. Leucocyte Typing IV: White Cell Differentiation Antigens. P798, 1078, Oxford University Press, New York
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York.
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