GLP-1 (clone 11E2), anti-mammal
€1,057.00
In stock
SKU
250365
Catalog Nr.: 250365
Size: 0.2 mg
Isotype: Mouse IgG2a
Applications: E, WB
Size: 0.2 mg
Isotype: Mouse IgG2a
Applications: E, WB
Protein Family: Hormones
Pathway and Disease: Carbohydrate Metabolism, Endocrine System, Metabolic Disorders, Signaling Molecules and Interaction
Description:
Glucagon-like peptide 1 (7-36)amide (GLP-1 (7-36)amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody reacts with all forms of GLP-1, including precursor.
Alternate Names: Glucagon-like peptide 1, GLP-1, Glucagon, GCG
Application Notes: Product Cat. No. 250365 binds to GLP-1 coated directly onto the microtiter well, and binds GLP-1 (7-36)amide in solution giving a Ka of 1.2x10E7 in inhibition ELISA. Product Cat. No. 250365 does not cross-react with coated glucagon or hGLP-2. No binding of free glucagon in solution is detected in inhibition ELISA, giving an estimated cross-reactivity <0.2%. E: 1:20,000; WB: 1:1,000
Accession No.: P01275
Antigen: Synthetic GLP-1(7-36)amide coupled to carrier and adsorbed onto aluminum hydroxide gel.
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
Pathway and Disease: Carbohydrate Metabolism, Endocrine System, Metabolic Disorders, Signaling Molecules and Interaction
Description:
Glucagon-like peptide 1 (7-36)amide (GLP-1 (7-36)amide) is the principal active form of GLP-1, the other being GLP-1 (7-37). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody reacts with all forms of GLP-1, including precursor.
Alternate Names: Glucagon-like peptide 1, GLP-1, Glucagon, GCG
Application Notes: Product Cat. No. 250365 binds to GLP-1 coated directly onto the microtiter well, and binds GLP-1 (7-36)amide in solution giving a Ka of 1.2x10E7 in inhibition ELISA. Product Cat. No. 250365 does not cross-react with coated glucagon or hGLP-2. No binding of free glucagon in solution is detected in inhibition ELISA, giving an estimated cross-reactivity <0.2%. E: 1:20,000; WB: 1:1,000
Accession No.: P01275
Antigen: Synthetic GLP-1(7-36)amide coupled to carrier and adsorbed onto aluminum hydroxide gel.
Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.
Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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