GLP-1 (clone ), anti-human, mouse, rat, mammal

GLP-1 (clone ), anti-human, mouse, rat, mammal

€966.00
In stock
SKU
251102
Catalog Nr.: 251102
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E
Protein Family: Hormones

Pathway and Disease: Endocrine System

Description:
Glucagon-like peptide 1 (9-36)amide and GLP-1 (9-37) are processed forms of GLP-1 that results from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, CD26, adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far. This antibody binds to the free N-terminus of GLP-1(9-36)amide and GLP-1 (9-37).

Alternate Names: Glucagon-like peptide 1, GLP-1, Glucagon, GCG, GLP-1(9-36)amide, GLP-1(9-37)

Application Notes: Product Cat. No. 251102 binds to the free N-terminus of GLP-1 (9-36)amide and GLP-1 (9-37) in solution. The antibody binds to GLP-1(9-36)amide (1 ug/ml) coated directly onto the microtiter well. Product Cat. No. 251102 as capture antibody binds to the N-terminus of GLP-1 (9-36)amide in a different manner that product Cat. No. 251103 does. Product Cat. No. 251102 can be used in a sandwich ELISA as capture antibody with product Cat. No. 251104 (biotinylated Cat. No. 250364) as detection antibody. Cross-reactivity of Cat. No. 251102 for GLP-1(7-36)amide is estimated at <3% based on inhibition ELISA. E: 1:6,000

Accession No.: P01275

Antigen: Synthetic [Cys19]-GLP-1(9-18) coupled to carrier

Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
More Information
Is Featured? No
Write Your Own Review
You're reviewing:GLP-1 (clone ), anti-human, mouse, rat, mammal